The phrase "at wits' end" refers to a state of extreme frustration or confusion. Its antonyms, therefore, include expressions that convey a sense of calmness or clarity. One such phrase is "in control," which suggests that one has a handle on a situation and is able to manage it effectively. Another antonym is "confident," which conveys a sense of assurance and self-assurance. A third phrase that can be used as an antonym for "at wits' end" is "in the flow," which suggests a state of effortless ease and a sense of effortless progress. Other possible antonyms for this phrase include "at ease," "in charge," and "in the zone.
