Being overfamiliar with someone or something could make them uncomfortable. However, there are several synonyms that you can use in place of "be overfamiliar with" to avoid this behavior. Some options include being too intimate, too friendly, too forward, too personal, too familiar, or too casual. You might also consider phrases like "crossing boundaries," "pushing limits," or "overstepping." By using these synonyms, you can communicate your meaning while maintaining a respectful distance and avoiding unwanted attention. Ultimately, it's important to be mindful of how your words and actions might be perceived by others to maintain positive relationships and avoid making anyone feel uncomfortable.