Gammaglobulinemia is a medical term used to refer to a condition characterized by low levels of gamma globulin in the blood. Gamma globulin is a type of protein that plays an important role in the immune system, helping to fight off infections and viruses. Some synonyms for gammaglobulinemia include immunoglobulin deficiency, hypogammaglobulinemia, and agammaglobulinemia. These terms are used interchangeably to refer to the same condition. Gammaglobulinemia can occur due to various factors, including genetic disorders, chronic diseases, and certain medications. Treatment is typically focused on boosting the levels of gamma globulin in the blood through medications or immunoglobulin replacement therapy.