The pyramided R gene is a term used in plant breeding to describe a method of incorporating multiple resistant genes into a single crop variety to provide greater protection against disease. Synonyms for this term may include stacked resistance genes, combined R genes, or multi-gene resistance. These synonyms emphasize the concept of combining several different resistance genes together to create a more effective defense against pathogens. This approach is particularly important in modern agriculture, as plant pathogens can quickly adapt and overcome single-gene resistance strategies. The use of pyramided R genes offers a more sustainable and long-term solution to crop protection, reducing the need for pesticides and promoting biodiversity.