What is another word for Adult Sandhoff Disease?
Pronunciation: [ˈadʌlt sˈandhɒf dɪzˈiːz] (IPA) 
Adult Sandhoff Disease is a rare genetic disorder primarily affecting the central nervous system. Also known as Late-Onset Sandhoff Disease, it is a progressive and debilitating condition caused by a deficiency of the enzyme β-hexosaminidase. Those afflicted experience a wide range of symptoms, including muscle weakness, ataxia, hearing and vision loss, and cognitive decline. Synonyms for Adult Sandhoff Disease include Late-Onset GM2 Gangliosidosis and Juvenile-Onset GM2 Gangliosidosis. These terms are used interchangeably to describe the same condition, emphasizing its late-onset manifestation and its similarity to Tay-Sachs disease, another storage disorder affecting lipid metabolism. Although treatments for Adult Sandhoff Disease are limited, ongoing research aims to better understand this devastating disease and identify potential therapies.
