Agomelatine is a medication that is primarily used to treat major depressive disorder. Some of the synonyms for agomelatine include TH-32, S20098 and Valdoxan. It is a unique medication due to its mechanism of action, which involves targeting both melatonin and serotonin receptors in the brain. Other antidepressants usually only target serotonin receptors, which can lead to unpleasant side effects. Agomelatine has been found to be very effective in treating depression, and it has fewer side effects than other medications. This makes it an excellent choice for patients who are looking for a safe and effective treatment option.