There are a variety of synonyms for the phrase "am off with you." Some similar expressions include "go away," "get out of here," "leave me alone," "get lost," "scram," "beat it," and "hit the road." These phrases all express a desire for someone to leave or go away, indicating a lack of interest or annoyance. Other related phrases with similar meanings might include "buzz off," "step off," "take a hike," or "back off." The choice of phrase might depend on the level of intensity or urgency of the situation, as well as the relationship and tone between the speaker and the person being addressed.