"Are destined" is used to describe events or outcomes that are unavoidable or predetermined. Some synonyms for this phrase include "are fated," "are predestined," "are predetermined," and "are assured." These phrases suggest that whatever is destined to happen will happen, regardless of any actions taken to prevent it. They imply a sense of inevitability, and often have a negative connotation. For example, one might say "we are fated to fail" or "the outcome is predetermined" when facing a difficult challenge with little hope of success. Regardless of the phrasing used, the idea of being destined conveys a sense of resignation and acceptance of a difficult fate.