The Asilomar Conference on Recombinant DNA, held in 1975, was a landmark event in the history of modern biotechnology. Synonyms for this significant conference include the Asilomar Conference on Genetic Engineering, the Asilomar Meeting on DNA Recombination, and the Asilomar Symposium on Gene Splicing. The conference brought together prominent scientists to discuss the safety and ethical concerns surrounding the new technology of recombinant DNA, which involved manipulating genes from different organisms. The outcome of the conference was a set of guidelines that established safety measures for genetic engineering experiments and paved the way for the responsible development of biotechnology. The legacy of the Asilomar Conference continues to shape the field of genetic engineering today.