Azetidine is a heterocyclic organic compound with a four-membered ring containing one nitrogen atom and three carbon atoms. There are several synonyms for this chemical compound, which includes azacyclobutane, 1-azacyclobutane, and tetramethyleneimine. Azetidine derivatives are widely used in organic synthesis, medicinal chemistry, and material science. Recently, there has been a surge in the development of azetidine-based drugs, as they exhibit a broad spectrum of biological activities, including anticancer, antiviral, and antibacterial properties. The exploration of novel azetidine derivatives has led to the discovery of several potent drugs that can be used as potential therapeutic agents for various medical conditions.