Big C refers to cancer, a serious and often life-threatening illness. The word itself can evoke fear and anxiety in those who hear it. However, there are synonyms that can be used in place of "big C" to make it less daunting. Some examples include malignancy, neoplasm, tumor, growth, and carcinoma. While these words still carry weight, they allow for a more clinical discussion of the disease, detached somewhat from the emotions that come with the term "cancer." By using synonyms, we can approach the concept of illness directly and unflinchingly, without getting lost in the fear it can inspire.