Brachmann De Lange Syndrome, also known as CdLS, is a rare genetic disorder that affects multiple organ systems and causes developmental disabilities. Additionally, it can result in distinct facial features, growth delays, and limb abnormalities. Although there are no direct synonyms for this syndrome, it is often referred to as CdLS or simply De Lange Syndrome. These terms can be used interchangeably to describe the same condition. Recognizing the seriousness of the disorder and using appropriate terminology helps in raising awareness and facilitating communication among medical professionals, researchers, and individuals affected by CdLS.