Bufagin is a toxic cardiac glycoside, a steroid obtained from the skin of toads. This compound has distinct chemical and pharmacological properties that make it useful in various scientific experiments, but it also presents potential hazards to human health. Synonyms for bufagin include bufagenin, bufotoxin, bufothionine, and bufotoxone. Each of these terms may be used interchangeably in referring to this powerful toxin. Despite its toxicity, bufagin has been studied for its potential benefits to treat some diseases such as certain types of cancer. However, due to the risk of toxicity associated with its use, caution must be taken when working with bufagin and its derivatives.