By route refers to the manner in which someone or something is proceeding. There are numerous synonyms for this phrase that can be used to express this concept in different ways. Several of the most common alternatives include "along the way," "via," "by way of," "through," "following," "using," "making use of," "traveling on," "taking," and "proceeding by." Each of these phrases highlights the idea of moving or progressing in a particular direction or method and can be used in a variety of contexts to convey the same meaning as "by route." By selecting the right synonym, writers and speakers can customize their language to better match their unique message and audience.