Carfuffle can mean a fuss or commotion, and there are several synonyms that can be used in its place. One common synonym is "kerfuffle," which refers to a chaotic situation or disturbance. Another option is "hullabaloo," which refers to a loud disturbance or uproar. "Commotion" and "uproar" are also synonyms that can be used interchangeably with carfuffle. "Pandemonium" is another word that is synonymous with carfuffle, and it is often used to describe a situation that is chaotic and disorderly. Alternatively, "tumult" is another synonym that can be used to describe a noisy and confusing situation.