Caudal regression syndrome is a medical condition that affects the development of the lower half of the body, including the spinal cord and legs. There are several synonyms for this condition, including sacral agenesis, congenital spinal agenesis, and caudal dysgenesis. These terms all refer to the incomplete development of the lower spine and associated structures. Symptoms may include paralysis or weakness in the legs, bladder and bowel dysfunction, and abnormalities in the genitalia. Treatment may involve surgery, physical therapy, and supportive care to manage symptoms. It is important for individuals with caudal regression syndrome to receive appropriate medical care to optimize their quality of life.