Central chorioiditis, a rare yet significant eye condition, is characterized by inflammation in the central region of the retina known as the chorioid. It can lead to vision impairment and discomfort. When discussing this condition, it is helpful to know a few synonyms that might be used interchangeably. These include central serous chorioretinopathy (CSCR), idiopathic central serous chorioretinopathy (ICSCR), central chorioretinal inflammation, and posterior multifocal placoid pigment epitheliopathy (PMPE). Each of these terms refers to the same fundamental ailment affecting the chorioid and retina. Being aware of these synonyms supports better understanding and communication among healthcare professionals, researchers, and patients striving to tackle this intricate eye condition.