Coloboma is a term used to describe a condition where there is an abnormality in the eye's structure resulting in a gap or a hole. There are several synonyms for the term "coloboma," such as optic fissure syndrome, fissure coloboma, and choroidal fissure cyst. These conditions can occur in various parts of the eye, such as the iris, retina, or optic nerve. Additionally, there are different types of coloboma, including uveal coloboma, which affects the choroid layer, and macular coloboma, which affects the central area of the retina. While coloboma is a rare condition, understanding its symptoms and its various synonyms is essential for early diagnosis and treatment.