Multiple sclerosis (MS), often referred to as combined sclerosis, is a chronic neurological disorder that affects the central nervous system. Synonyms for MS include disseminated sclerosis, encephalomyelitis disseminata, and demyelinating inflammatory disease. These terms describe the characteristic nature of this condition, where inflammation and damage occur to the protective covering of nerve fibers (myelin) in the brain and spinal cord. Due to this damaging process, individuals with MS experience a wide range of symptoms, including fatigue, weakness, balance problems, and cognitive impairment. Recognizing the various synonyms and terminologies associated with combined sclerosis helps facilitate communication, research, and raise awareness about this debilitating condition.