Copy-number variation (CNV) refers to a phenomenon that pertains to the deletion, duplication, and other structural variations of genetic information in the genome. While the term CNV is widely accepted and used, there are synonyms that can be used interchangeably to describe the same phenomenon. Some of the synonyms for CNV include copy number alterations (CNA), gene dosage variations (GDV), genomic amplification, genomic deletion, and copy variation. These synonyms help in understanding and explaining the genetic variations that occur in organisms. The use of synonyms is useful in avoiding repetition and confusion when describing genetic abnormalities and variations in the genome in various research studies and scientific literature.