Cornelia De Lange Syndrome (CdLS), also known as Brachmann de Lange Syndrome, is a rare genetic disorder that affects multiple organ systems and causes a range of physical, intellectual, and developmental challenges. While there aren't direct synonyms for CdLS, it is sometimes referred to as De Lange Syndrome or Brachmann Syndrome. These terms are used interchangeably to describe the same condition. CdLS is characterized by distinct facial features, such as thin eyebrows, long eyelashes, and microcephaly. It can also lead to growth delays, limb abnormalities, hearing loss, and cognitive impairments. Early diagnosis and intervention are crucial in managing this complex condition and improving the quality of life for individuals affected by it.