Cushing's Syndrome is a hormonal disorder caused by prolonged exposure to high levels of cortisol hormone. Some synonyms for this syndrome include hypercortisolism, adrenocortical hyperfunction, and hyperadrenocorticism. These terms refer to the same medical condition but are used interchangeably to describe the excessive production of cortisol hormone. The symptoms of Cushing's Syndrome include weight gain, fat deposits in the face, neck, and upper back, high blood pressure, and weakened immune system. It can be treated by removing the source of cortisol production or by taking medications to reduce cortisol levels. Early diagnosis and treatment are essential to preventing the complications of this syndrome.