Cystoid macular edema (CME) is a medical condition that causes swelling in the macula, the central part of the retina. Synonyms for CME include macular edema, diabetic macular edema, retinal edema, and uveitic macular edema. These terms are often used interchangeably in medical literature and refer to the same condition. Symptoms of CME include blurred or distorted vision, difficulty reading or performing close-up tasks, and sensitivity to light. Causes of CME vary, but it is commonly associated with diabetes, inflammatory diseases, and certain medications. Treatment options include anti-inflammatory medications, laser therapy, and surgery. Early diagnosis and prompt treatment are crucial in managing CME and preventing permanent vision loss.