Cytomegalovirus infection, commonly known as CMV infection, is a viral disease that can cause various symptoms like fever, body aches, and fatigue. CMV infection can affect people of all ages, primarily those with a weak immune system, such as newborns, pregnant women, and people with HIV/AIDS. Due to its complex medical term, CMV infection is often referred to as HCMV, human herpesvirus 5, or Cytomegalic inclusion disease. Other synonyms for CMV infection may include CMV disease, cytomegalovirus syndrome, or congenital CMV infection. Early diagnosis and treatment of CMV infection are crucial to prevent severe complications, especially in vulnerable populations.