Cytoplasmic polyadenylation element (CPE) refers to a regulatory RNA element found in the 3' untranslated region (3'UTR) of specific messenger RNAs. CPE is responsible for controlling the translation of the mRNA into proteins. It affects poly(A) tail elongation, which plays a crucial role in the translation of mRNAs. These elements are also found in some non-coding RNAs and in select viral RNAs. Some synonyms for CPE include cytoplasmic poly(A) sequences, poly(A) signal elements, cytoplasmic deadenylase elements, and untranslated region regulatory motifs. These various names all refer to the same element that plays a central role in regulating gene expression and protein synthesis.