De Soto is a proper noun that refers to Hernando de Soto, a Spanish explorer who was prominent during the 16th century. Therefore, there are no synonyms for this name. However, there are other ways to describe de Soto's expeditions, such as "Spanish exploration of the southeastern United States" or "de Soto's travels through the New World." Additionally, de Soto's journey was a significant moment in history, often referred to as the "de Soto expedition." Although there are no synonyms for de Soto's name, there are several alternatives to describe or refer to his expedition, and its legacy in history.