De-fuses is a verb that means to reduce the intensity of a situation or to calm it down. The word de-fuses can be expressed in several other ways depending on the context in which it is used. To amplify or intensify a situation could be considered to be the opposite of de-fuses, as it would make it more heated or charged. Other antonyms of de-fuses include aggravate, escalate, provoke, enflame, rouse, arouse, stimulate, excite, agitate, incite, inflame, or stir up. These words suggest that a situation, instead of being calmed, is being made worse or are becoming more intense.