A depolarizing pre-pulse is a neurological term that refers to a stimulus which causes depolarization of nerve cell membranes. This typically leads to an increase in the excitability and responsiveness of neurons. Synonyms for this term might include "activating pre-pulse," "priming stimulus," or "facilitating impulse." These alternative phrases all convey the idea that the pre-pulse is preparing the neurons for a subsequent, more significant stimulus. Other possible synonyms might depend on the context in which the term is used, such as "pausing pre-pulse" or "inhibitory stimulus" if the goal is to reduce neuron activity rather than enhance it. Regardless of the specific phrasing, the concept of depolarizing pre-pulses plays a significant role in many neurological processes.