Disavail, a word rarely used in everyday conversation, can be easily substituted with synonyms that are far more familiar. One such synonym is "inconvenience", as both words imply a sense of trouble or hindrance. Additionally, the word "obstacle" can replace "disavail" if one wants to convey the idea of an impediment that obstructs progress. Another synonym worth considering is "hindrance", which implies something that causes delay or obstruction. Finally, the word "disadvantage" can be used interchangeably with "disavail" if one wishes to convey a sense of unfavorable circumstances. These synonyms not only provide alternatives for the word, but also make communication clearer and more comprehensible.