Distomatosis is a medical condition that affects livestock and wildlife. It is commonly known as liver fluke disease and is caused by parasitic flatworms. These worms inhabit the liver of their host, causing severe damage and sometimes death. There are several synonyms for distomatosis, including fasciolosis, hepatic fascioliasis, and fascioliasis. These terms are often used interchangeably to refer to the same disease. While distomatosis is common in many regions of the world, it can be prevented through proper animal husbandry practices. Regular deworming and proper hygiene can help to reduce the risk of infection in herds and flocks.