There are many synonyms for the phrase "do someone wrong" that convey a sense of injustice or harm done to someone. One synonym is "mistreat," which implies that someone has been treated unfairly or without respect. Another synonym is "harm," which suggests that someone has been physically or emotionally injured by another person's actions. Others include "offend," "betray," "injure," and "disrespect." These synonyms highlight the negative impact of someone's actions on another person. It is important to recognize these actions and stand up against them when they occur to prevent further harm.