Dornase alfa is an enzyme medication that is used to treat people with cystic fibrosis. The drug works by breaking down thick mucus that is found in the lungs of people with this condition. There are a few different synonyms for this medication, including Pulmozyme, DNase, and recombinant human deoxyribonuclease. Each of these terms refers to the same medication and can be used interchangeably. While dornase alfa is a relatively new medication, it has proven to be effective in helping people with cystic fibrosis manage their symptoms and improve their quality of life. If you or someone you know is struggling with this condition, talking to a doctor about the benefits of dornase alfa could be a wise choice.