Dost business with is comprised of two elements, 'dost' meaning a close friend or companion, and 'business' which refers to commercial activity. The antonyms, therefore, must be words that are opposite in meaning to both these elements individually and as a whole. Words such as 'enmity', 'hostility', 'dislike', 'animosity', 'antagonism' would be appropriate antonyms for 'dost', indicating a lack of friendship or camaraderie. Similarly, 'leisure', 'pastime', 'hobby', 'recreation' are antonyms for 'business', denoting a relaxed, non-commercial activity. Collectively, antonyms for dost business with would imply avoiding connections or dealings with someone, possibly due to personal differences or lack of interest in commercial affairs.