'Double minute' is a term commonly used in medical science and refers to a particular type of extra-chromosomal DNA fragment present in certain cancerous cells. However, there exist many synonyms for this term, which include 'double minute chromosome', 'DM', 'd-min', 'd-min chromosome', and 'd-chromosome', amongst others. These synonyms are used interchangeably by researchers and medical professionals, with each carrying the same meaning as 'double minute'. Since these extra-chromosomal fragments play a critical role in cancerous cells' growth and proliferation, understanding the various terminologies used to describe them is crucial for effective treatment and management of cancer.