The phrase "drive nuts" means to irritate or frustrate someone to the point of driving them crazy. There are several synonyms for this phrase that can be used to add variety to your writing or conversation. Some alternatives include exasperating, infuriating, agitating, annoying, provoking, and vexing. Each of these words carries a slightly different connotation, allowing you to choose the one that best fits your intent. Using synonyms can help prevent repetition in your speech or writing, which can make you sound more thoughtful and educated.