Dukes disease, also known as familial adenomatous polyposis (FAP), is a hereditary condition characterized by the development of numerous polyps in the colon and rectum. These polyps have the potential to become cancerous, making early detection and intervention essential. Familiarizing oneself with alternative terms for Dukes disease can aid in knowledge expansion and better communication. Synonyms for this condition include familial polyposis coli, familial polyposis, and Gardner syndrome. Understanding these alternate names can enhance discussions among healthcare professionals, patients, and their families. Recognizing these synonyms can assist in accurate diagnosis, effective treatment, and disease management, ultimately contributing to improved quality of life for individuals affected by Dukes disease.