The Family Schistosomatidae is a group of parasitic flatworms found in freshwater snails and vertebrate hosts, including humans. Commonly known as the blood flukes, these parasites cause schistosomiasis, a debilitating and chronic disease that affects millions of people worldwide. Synonyms for this family include Schistosoma family, Trematoda family, flatworm family, and digenetic fluke family. The Schistosomatidae family includes several species, each with unique morphological and biological characteristics. Understanding the taxonomy and diversity within this family is essential for the development of effective control measures and treatments for schistosomiasis.