The "foramen of Magendie" is a crucial anatomical structure situated in the fourth ventricle of the brain, responsible for the drainage of cerebrospinal fluid. There are various synonyms for this term, which highlight its significance and functions. It is often referred to as the "median aperture", representing its position in the midline of the cerebellum. Additionally, it is commonly known as the "apertura mediana ventriculi quarti", emphasizing its role as an opening in the fourth ventricle. Moreover, it is sometimes called the "Magendie's hole", honoring the French physiologist François Magendie, who first identified and described this vital passage. Overall, these synonyms effectively illustrate the importance of the foramen of Magendie in the cerebrospinal fluid dynamics of the brain.