Fukuhara Disease, also known as progressive external ophthalmoplegia with mitochondrial DNA deletions, is a rare genetic disorder affecting mitochondrial function. Although there are no commonly used synonyms specifically for Fukuhara Disease, it falls under a broader category of mitochondrial diseases. These may include conditions like mitochondrial myopathy, Kearns-Sayre syndrome, or Pearson syndrome. Mitochondrial diseases are characterized by impaired energy production in cells, leading to various organ dysfunctions. While Fukuhara Disease possesses distinct clinical features, common synonyms more often refer to the umbrella term of mitochondrial disorders, as the specific condition is relatively less well-known. Early diagnosis and comprehensive medical management are crucial in mitigating the impact of such conditions on affected individuals.