Fungaemia is a medical condition in which the bloodstream is infected by fungi. It is a serious and potentially life-threatening condition that requires prompt treatment. There are several synonyms for fungaemia, including systemic fungal infection and disseminated mycosis. Other terms used to describe fungal infections in the bloodstream include candidaemia, aspergillosis, and cryptococcosis. Identification and treatment of the underlying fungal infection is important for the successful management of fungaemia. Antifungal medications are commonly used to treat the infection and prevent further spread, while supportive care may be necessary to manage complications. Early diagnosis and treatment are crucial for the best possible outcome.