General paresis is a progressive neurosyphilis disease that adversely affects a person's mental and physical abilities. It is also known by many other names such as general paralysis of the insane, progressive paralysis, dementia paralytica, syphilitic dementia, and more. These synonyms were given based on the disease's various symptoms, such as insanity, dementia, paralysis, and general weakness. General paresis was very high in the early 1900s, but with the right treatment and medication, it is now a rare disease. If you or someone you know is experiencing any of the symptoms of general paresis, you should seek advice from a medical professional.