Genus Coptis, commonly known as Goldthread or Canker Root, belongs to the family Ranunculaceae and is native to Asia, North America, and Europe. This genus is known for its medicinal properties and is traditionally used for treating gastrointestinal and other health-related issues. Coptis has several synonyms, including Rhizoma Coptidis, Goldenseal, Huang Lian, and Chinese Goldthread. These synonyms are used interchangeably to identify the same herb across different regions and traditions. Goldenseal, in particular, is believed to be a close cousin of Coptis, both having similar therapeutic benefits. Other common synonyms for Coptis include Yellow Root, Mouth Root, and Cut Leaf. These synonyms help herbalists and Traditional Chinese Medicine practitioners to identify and administer this beneficial herb effectively.