The phrase "give the lie to" means to expose a falsehood or prove something to be untrue. There are several synonyms for this phrase that can be used in different situations. One such word is "refute" which implies proving an argument or statement to be wrong. Another synonym is "debunk," which refers to the process of exposing a myth or misconception. The word "contradict" can also be used in this context, indicating that something opposes or goes against what was previously said. Additionally, "disprove" and "negate" can be considered synonyms for "give the lie to." Whichever word is used, the intention behind them is to reveal the truth and set the record straight.