When it comes to the phrase "go off with," there are numerous synonyms that can be used to convey a similar meaning. One option could be "run away with," which implies a sudden departure and may carry an element of excitement or spontaneity. Another possible synonym is "abscond with," which connotes a more deliberate and perhaps even illicit departure. Other alternatives might include "depart with," "leave alongside," or "take along with." Ultimately, the choice of synonym will likely depend on the context and tone of the sentence in which it is used, as well as the writer's personal style preferences.