When things "go out of control," it implies a sudden and unexpected shift from manageable to unmanageable. Thankfully, there are several synonyms to describe this phenomenon. "Spiral out of control" suggests a rapid downward descent or inability to stop a negative chain reaction. "Run amok" implies a wild, reckless, or violent state of affairs. "Get out of hand" suggests something has escalated beyond what is manageable or acceptable. Finally, "lose one's grip" is a more self-referential way to describe going out of control, implying a loss of control over oneself rather than external circumstances. No matter which synonym you choose, all describe a situation where things have gone awry.