Gray platelet syndrome (GPS) is a rare bleeding disorder characterized by the lack of alpha-granules in platelets. This condition leads to abnormal platelet function, resulting in easy bruising and bleeding. Some synonyms for GPS include alpha-granule deficiency syndrome, gray platelet alpha granule defect, and gray thrombocytopenia. Symptoms of GPS can also include nosebleeds, heavy menstrual periods, and excessive bleeding after dental or surgical procedures. Treatment for GPS typically involves managing the bleeding symptoms with blood transfusions, medications, and close monitoring. It is important for individuals with GPS to work closely with their healthcare team to develop an appropriate treatment plan and prevent long-term complications.