Guaiacum sanctum, commonly known as Holywood Lignum-Vitae or Holywood Guaiacum, is a tree species found in the Caribbean and coastal regions of South and Central America. The tree's dense, hard, and durable wood has been traditionally prized for its medicinal and decorative properties. Some synonyms for Guaiacum sanctum include greenheart, ironwood, and bulnesia. The wood of this tree is also used in the manufacture of artisanal crafts and musical instruments such as maracas, drums, and xylophones. The tree's resin and bark have been used in traditional medicine to treat various ailments such as arthritis, rheumatism, and syphilis. Despite having many synonyms, Guaiacum sanctum remains a unique and important species to the region's ecology and heritage.