Handled roughly can be replaced with its antonyms, which suggest a gentler and more careful approach. The first antonym is delicately, which means to handle something with great care, sensitivity and gentleness. Another antonym for handled roughly is smoothly, which implies treating something in a calm and composed manner, without jerks or sudden movements. Treated carefully is another opposite of handled roughly, indicating that something is handled with utmost care, attention and delicacy. Respectfully is another antonym for handled roughly, indicating that something is treated with admiration and honor, rather than with disdain or violence. Whatever the antonym, they all indicate that something is handled with great care, sensitivity and respect.