The phrase "hard-luck guys" refers to individuals who seem to face misfortune, bad luck or difficult challenges on a regular basis. Synonyms for this phrase may include terms like underdog, victim or ill-fated. Other options could be unlucky fellows, hapless souls, tough break recipients, or the unfortunate. These words all share the same sense of describing individuals who are struggling, disadvantaged or facing uphill battles. Whether it's in life or in a specific situation, these synonyms capture the same feeling of empathy and compassion for those who are facing difficulties or challenges beyond their control.