The term "Harlequin Fetus" refers to a rare and severe genetic disorder known as Harlequin Ichthyosis. This condition results in the formation of thick, diamond-shaped scales that cover the baby's body, resembling a harlequin costume. Although the term "Harlequin Fetus" is widely recognized, it is not preferred due to its negative connotations. Instead, medical professionals use alternative terms such as Harlequin Ichthyosis or Ichthyosis Congenita, to describe this condition more accurately. These synonyms ensure a more respectful and sensitive approach when discussing the unique challenges faced by individuals and families affected by this condition, fostering empathy and understanding within the medical community.